Técnicas de micro/nanoencapsulação de produtos naturais extraído do cerrado: oleo de buriti

Abstract

Buriti oil has high added value mainly due to its high concentration of β-carotene, that is already known for its healing, photoprotective, anti-inflammatory and antibiotic effects. However, the use of oils in medicines, cosmeticS and foodS have certain stability issues regarding high temperatures and light. In addition, there are other factors such as low water solubility, undesirable sensory effects and low bioavailability. In order to circumvent such problems, the use of oil encapsulation can contribute to its stability, improving its availability. The encapsulation can be filtered in micro and nanoencapsulation. Among the various techniques to preparing micro and nanostructured systems, some were used for the encapsulation of buriti oil. Using the spray-drying method, microparticles were formed, composed of a complex of PGB and PAM and buriti oil, and also formed by clove extract, buriti oil, Compritol ®️ 888, ATO, Poloxamer 188. Through the technique of coacervation followed by spray-drying, it is possible to obtain microparticles containing 200 μm medium-sized buriti oil. Nanoemulsions containing buriti oil can be prepared by means of ultrasonic emulsification, obtaining particles with an average size of 142.11 ± 0.92 nm and low polydispersity; using the phase inversion temperature, it is obtained average droplet size (73–86 nm) and polydispersity (0.08–0.15); and finally, by high pressure homogenization, being processed for 3 cycles at 800 bar, and modeling with an average size of 200 nm. CLN containing buriti oil are formed mainly by high pressure homogenization, and the particle size ranged from 400 to 700 nm, depending on the degree of fatty acid esterification not present in buriti oil. Finally, it is possible to obtain polymeric nanoparticles smaller than 100 nm with spherical morphology containing buriti oil using the spontaneous emulsification technique followed by lyophilization, with coating material composed of swine gelatin and Tween 20. Thus, the choice of method and technique used in the collection of particles to encapsulate oils and other natural compounds of Cerrado, such as buriti oil, depends on the type and composition of the particles, the machinery and equipment available, the stability of the compounds regarding temperature and also to the use of organic solvents.