Infecção natural por Cryptococcus gattii em porquinho-da-índia (Cavia porcellus) : relato de caso

Abstract

Cryptococcus gattii, was recently understood as a distinct species of Cryptococcus neoformans due to different phenotypic, biochemical, serological and ecoepidemiological characteristics. Its pathogenicity and complexity in the treatment demonstrates the importance of the previous diagnosis and the importance of the knowledge of this saprozoonosis. Considering the eco-epidemiology of C. gattii, its cosmopolitan action, and the increasing ascent by several regions, a case of natural infection of this pathogen was reported in a guinea pig (Cavia porcellus) raised as na unconventional pet in a central area of the state capital of Mato Grosso, as well as the diagnosis through fine needle aspiration cytology and fungal culture of the palpebral lesion, together with the confirmation of the species by PCR (Polymerase Chain Reaction) and sequencing from biopsy tissue. In addition to the therapeutic approach adopted successfully in the treatment of the disease through the use of itraconazole, this work aims to elucidate the possible sources of infections, to elaborate prevention measures and effective therapy when necessary.