Estudo retrospectivo de trombocitose em cães

Abstract

Thrombocytosis is the increase in the number of platelets per microliter (μL) of blood and counts greater than 1.000.000/μL may be associated with clinical signs of bleeding or thrombosis. It may occur primarily in myeloproliferative conditions, or as a secondary (reactive) response in a variety of physiological and pathological states. The present study aimed to review 12.676 dog blood counts in order to define the main diseases or clinical conditions associated with thrombocytosis within two years. According to the diagnosis, each dog was inserted into one of the following categories of diseases or clinical condition: neoplasms, gastrointestinal, endocrine, ophthalmologic, trauma and surgeries, dermatological, cardiac, neurological, infectious, respiratory, genitourinary, idiopathic, multiple and gestation. The prevalence of thrombocytosis in this study was 4,5%. Mean platelet counts in all diagnostic categories were similar, with no significant difference between them (P≥0.05). The disorders most commonly associated with thrombocytosis were gastrointestinal diseases followed by neoplasms. In addition, increases in platelet counts were observed in dogs treated with glucocorticoids and vincristine. As for the degree of severity, extreme thrombocytosis occurred more associated with gastrointestinal diseases.