Modulação pelo melão-de-são-caetano (momordica charantia) do perfil oxidativo das células e correlação com parametros hemoreologicos

Abstract

Momordica charantia belongs to the family Cucurbitaceae, and is popularly known as São Caetano melon, it is a herbaceous plant, climbing, ruderal and reproduced by seeds. Historically, Momordica charantia is among one of the most important groups that contains species applied in the production of herbal medicines. The benefits are in the fruits, seeds, leaves and roots that are applied in the use of diabetes, healing, colic treatment, such as anthelmintic, anti-rheumatic, and anti-carbuncolose and can also be indicated for the treatment of hemorrhoids, tumors, boils, morphea, eczema and blackheads. The objectives of the study are to evaluate the release of SOD and to characterize rheologically the flow curves and blood viscosity with the presence of melon of São Caetano in two different concentrations 40µg /mL e 4µg/mL. The peripheral blood was incubated with the extract and the SOD release was evaluated and the rheological characterization of the groups that contained the extract of São Caetano melon with the control group, which was the group that contained only a blood sample. The results obtained were that both groups that received the extract of São Caetano melon showed no change in blood viscosity and the flow curve did not change either, their nonNewtonian behavior remaining with the presence of São Caetano and hears stimulation of SOD release in MN cells. It is concluded that the extract of melon-de-são-caetano showed antioxidant effects and does not alter the flow curve and blood viscosity in the analyzed concentrations, being able to be an effective immunomodulator in the protection of MN cells.