Efeitos da suplementação de vitamina D em pacientes com covid-19 : uma revisão integrativa

Abstract

Introduction: The worldwide problem of the coronavirus pandemic brings the search for adjuvant therapies for the treatment of infection caused by COVID-19. In this scenario, we seek an investigation regarding the real effects of vitamin D supplementation in patients hospitalized with the virus. Objective: In this review, we will discuss the most recent evidence of the effects of vitamin D supplementation on diseases and complications of the pathogenicity of COVID-19. Method: This is an integrative review, scientific articles were searched in the Pubmed and Scielo Brasil databases, between the months of January 2020 and August 2021. Results: A limited number of clinical trials, observational studies and randomized studies, suggest a possible association between serum vitamin D concentrations and the clinical picture of COVID-19, however, these studies differ in terms of experimental design, sample size and the outcomes assessed, which makes it impossible, among other things, to carry out an accurate comparative analysis of the body of evidence. Conclusion: Therefore, well-designed studies that clearly and objectively demonstrate the role of vitamin D in the prevention and/or treatment of COVID-19 are still needed.