Efeito do óleo de algodão sobre células do câncer de mama MCF-7

Abstract

Cotton (Gossypium hirsutum) is the main product used in the textile industry, and is a strong candidate for use as biodiesel. Cotton oil has antioxidant effects due to its composition that helps to reduce free radicals, which are one of the main causes of the appearance of tumor cells. Breast cancer is one of the most common diseases today with a high incidence and mortality, being the leader with the highest incidence and high mortality rate worldwide. This study aims to evaluate the tumoricidal effect and the static effect on tumor growth of degummed cottonseed oil at different concentrations on breast cancer cells of MCF-7 strain through cell viability after 2 and 24 hours of incubation. It was noticed that the cell viability of MCF-7 cell culture samples in the presence of the stimulus after 2 hours of incubation had a difference in micro concentration of 29.83%, in the nano and pico concentration there was also a decrease in cell viability compared to the control verifying tumoricidal effect, it was also observed a subtle reduction in cell viability of MCF-7 cell culture samples in the presence of cottonseed oil after 24 hours of incubation conferring a static effect on tumor growth. In view of the results of this study, future studies can be carried out to improve the use of cottonseed oil as an immunomodulator.