Acne vulgar: tratamentos convencionais e a base de subprodutos de plantas medicinais

Abstract

Acne is a very common chronic dermatosis characterized by affecting the skin's pilosebaceous follicle. The aim of this work was to evaluate possible herbal treatments for acne vulgaris. Literature survey was carried out mainly using Pubmed, Sciencedrect and Google Scholar. The sebaceous hyperproduction, follicular hyperkeratinization, increased colonization of Propionibacterium acnes and periglandular dermal inflammation are the main factors to acne. The treatment is based on the severity and type of acne. Mild to moderate acne is typically treated topically with retinoids, acids, and benzoyl peroxide. More severe forms require systemic treatment that may include antibiotics, retinoids and antiandrogens. Anti-acne phytocosmetics are produced from active ingredients from medicinal plants that have wound healing, antimicrobial, anti-inflammatory, antiseptic and analgesic activities. are Flavonoids, tannins, saponins, coumarins, terpenes and essential oils are the most active phytochemical compounds in the treatment of acne. Currently, many plants have been researched, including Melaleuca alternifolia, Aloe vera, Garcinia mangostana, Arctium lappa, Cymbopogon Citratus and Camellia sinensis, among others. All are rich in one or more classes of phytochemical compounds active against acne. We consider medicinal plants are a rich field for new anti-acne products. There is a lot of research on the feasibility of using plant products, but more in vivo studies using volunteers are needed. Furthermore, many studies lack the comparison of activity with any substance conventionally used in treatment.