Correlação das infecções causadas pelo vírus do papiloma humano com os casos de câncer de boca e orofaringe no Mato Grosso

Abstract

The human papillomavirus (HPV) is a virus with DNA genome belonging to the Papillomaviridae family which causes infections in epidermis and mucous tissue that can lead to the formation of benign or malignant neoplasms. Often found in the anal and genital region it is also associated with the mucosa and sometimes with papillomatous lesions such as condyloma, papilloma, leukoplakia, lichen planus and carcinoma, especially squamous cell carcinoma (SCC). The various studies developed to date have not been able to accurately clarify the role of HPV in oral carcinogenesis, but the role of HPV has become evident every year, as well as advances in viral detection techniques in the oral mucosa. In this study, a literature review was carried out to correlate the presence of human papilloma virus (HPV) in cases of cancer of the oral cavity and oropharynx, aiming to increase knowledge about this subject.