Avaliação dos parâmetros hemorreológicos do extrato etanólico de Strychnos pseudoquina

Abstract

Medicinal plants are those that have bioactives capable of bringing benefits to their handler. The use of plants in an alternative way is an empirical practice that was used by many ancient peoples and extends to the present day. The Quina do cerrado, is a plant from the Brazilian cerrado and that belongs to the Loganiacea family, it is known by several popular names, such as: "quina-branca", "quina-quina", "Quina do cerrado" and among other names. The most used parts of this plant are the leaves and the bark. People use it for liver problems, stomach problems, malaria and anemias. Rheology is an area of physics that studies the deformation of different materials. Fluids are also an object of study in rheology, where they will be classified according to their behavior into Newtonian fluids and non-Newtonian fluids. The aim of this study was to evaluate the rheological parameters of the ethanolic extract of Quina from the cerrado on peripheral blood, and also to evaluate the flow and viscosity curves of the hemorrhological parameters in the presence of quina extract in different concentrations. For this, blood samples were collected from 4 clinically healthy people, aged 23 to 57 years. The blood samples were added to different dilutions of the ethanolic extract of S. Pseudoquina and then taken for rheological analysis. The results showed that the blood presents a non-Newtonian behavior and with indications of thixotropy, and that the extract of Quina from the cerrado in the blood in the three concentrations analyzed did not present significant differences when statistically analyzed, thus making the extract biocompatible with the blood.