Associação tópica de sulfadiazina de prata com DMSO puro para tratamento de dermatite piogranulomatosa por Streptomyces sp em lobo guará (Chrysocyon brachyurus)

Abstract

Streptomyces is a gram-positive, filamentous bacteria, hardly described in the veterinary casuistry, but is commonly found as contaminant in bacterial isolates. Streptomyces infections requires long term treatment and has low cure rate, with the possibility of recurrence. A maned wolf at UFMT Zoo, while in its third recurrence of localized dermatitis, characterized by multiple ulcerated, pinkish, raised and irregular skin lesions with subcutaneous pockets of viscous contents, was diagnosed with Streptomyces sp piogranulomatous dermatitis, after histopathological examination, isolation and genetic sequencing. The treatment instituted was systemic sulfamethoxazole + trimethoprim daily and silver sulphadiazine associated with pure DMSO topically after a wound cleansing, every three days. At the end of the treatment, the patient had complete improvement of the cutaneous lesion, with no further recurrences.