Efeitos do chá verde sobre o perfil metabólico de camundongos Swiss com obesidade induzida por dieta hiperlipídica

Abstract

The increase in obesity and its comorbidities represent a big public health problem in all over the world. Some studies have shown that polyphenols in the green tea help on weight loss and improve metabolic parameters. So, this work proposed to review the Green Tea Administration Effect (Camelia sinensis) on biochemical and nutritional parameters in obese Swiss’ mice with fat-diet’ induced. It’sused 20 Swiss mice, Young Male, exposed a high-fat diet or balanced diet during 8 weeks, later it was given green tea by gavage, during successive 28 days. It’s apllied tolerance test glucose to evaluate the metabolism and its effects. The animals treated with the green tea wasn’t presented changes on food intake, body weight, retroperitoneal adipose tissue and liver fat, however they’re exhibited reduction of brown adipose tissue weight, triglycerides. They also SHOWED an improvement at tolerance to glucose, independently dietary treatment. The reduction of cholesterol was observed only in the group that received a balanced diet associated with green tea. Therefore, for obesity model induced by high fat diet, green tea was able to improve some metabolic parameters, however with no significant effects on body weight and food consumption.