Efeitos do consumo de óleo de coco em ratos na fase de crescimento sobre o perfil nutricional e metabólico na vida adulta

Abstract

In humans, the use of coconut oil in food preparation has been studied as an adjunct in the treatment of obesity due to its possible thermogenic effect, which could influence the weight loss. The effects of coconut oil consumption in rats in the growth phase on the nutritional and metabolic profile in adulthood. The animals were divided into two groups according to the type of received diet: Control Group (CG) and Test Group (WG). GT mice showed an increase in deposits of epididymal fat, despite similar weight gain between the groups and lower energy consumption compared to GC rats. The messenger RNA of UCP-1 in brown adipose tissue and KITT were lower in GT compared to the CG. Serum concentrations of HDL cholesterol, albumin and ketone bodies, and the ratio urea / creatinine were higher in GT group compared to the control group. Therefore, consumption of coconut oil in normal amounts in the diet caused a positive energy balance, visceral fat deposition, insulin resistance, ketonemia and cellular dehydration signals.